Submissions from 2024
Total Synthesis of (-)-Rauvomine B via a Strain-Promoted Intramolecular Cyclopropanation, Jake M. Aquilina, Ankush Banerjee, Gabriel N. Morais, Shuming Chen, and Myles W. Smith
Activity-Based Protein Profiling of RHBDL4 Reveals Proteolysis of the Enzyme and a Distinct Inhibitor Profile, Cassondra C. Davies, Ren-Ming Hu, Paul J. Kamitsuka, Gabriel N. Morais, Regina Stasser de Gonzalez, Katelyn A. Bustin, Megan L. Matthews, and William Parsons
Constitutive Activation of RpoH and the Addition of L-arabinose Influence Antibiotic Sensitivity of PHL628 E. coli, Jenna K. Frizzell, Ryan L. Taylor, and Lisa Ryno
Intermolecular hydrogen bonding behavior of amino acid radical cations, Isabella Moppel, BarbaraAnn Elliott, and Shuming Chen
Pd/IPrBIDEA-Catalyzed Hydrodefluorination of gem-Difluorocyclopropanes: Regioselective Synthesis of Terminal Fluoroalkenes, Huijun Qian, Zachary P. Cheng, Yani Luo, Leiyang Lv, Shuming Chen, and Zhiping Li
Carbon Adsorbent Properties Impact Hydrated Electron Activity and Perfluorocarboxylic Acid (PFCA) Destruction, Hosea A. Santiago-Cruz, Zimo Lou, Jiang Xu, Ryan C. Sullivan, Bailey B. Bowers, Rachel A. Molé, Wan Zhang, Jinghao Li, Joshua S. Yuan, Susie Y. Dai, and Gregory V. Lowry
NMR-guided refinement of crystal structures using 15N chemical shift tensors, Ryan Toomey, Luther Wang, Emily C. Heider, Joshua D. Hartman, Alexander J. Nichols, Dean A.A. Myles, Anna S. Gardberg, Garry J. McIntyre, Matthias Zeller, Manish A. Mehta, and James K. Harper
Development of a diverse activity-based probe library for studying serine proteases, Charles Wilber, Regina Stasser de Gonzalez, Dat Nguyen, Jay Aghanya, Heewon Seo, and William Parsons
Submissions from 2023
Optimized derivatization of primary amines with the fluorogenic reagent naphthalene-2,3-dicarboxaldehyde toward reproducible quantitative analysis in biological systems, Paola Gonzalez Quevedo, Elizabeth L. Rigby, Samuel Kearney, and Rachel A. Saylor
Chemoselective Quinoline and Isoquinoline Reduction by Energy Transfer Catalysis Enabled Hydrogen Atom Transfer, De-Hai Liu, Kyogo Nagashima, Hui Liang, Xue-Lin Yue, Yun-Peng Chu, Shuming Chen, and Jiajia Ma
Chemo-, Stereo- and Regioselective Fluoroallylation/Annulation of Hydrazones with gem-Difluorocyclopropanes via Tunable Palladium/NHC Catalysis, Huijun Qian, Hieu D. Nguyen, Leiyang Lv, Shuming Chen, and Zhiping Li
To Fluoresce or Not to Fluoresce: Investigation of Structural and Fluorescence Characteristics of CBI-Dopamine, CBI-Serotonin, and Their Structural Analogs, Elizabeth L. Rigby and Rachel Saylor
Submissions from 2022
(C5H6N)Pb2X5 (X = Cl, Br): Hybrid Lead Halides Based on Seven-Coordinate Pb(II), Alyssa S. Chow, Xinyue Zhong, Douglas H. Fabini, Matthias Zeller, and Catherine M. Oertel
The Effects of Humidity on Spontaneous Cocrystallization: A Survey of Diacid Cocrystals with Caffeine, Theophylline, and Nicotinamide, Riley D. Davies, Nicolas J. Vigilante, Aaron D. Frederick, Venkata S. Mandala, and Manish A. Mehta
Kinetics Study of Acid-Catalyzed Sulfate Esterification Reactions for Atmospherically Relevant Polyols, Matthew Elrod
Cyclometalated Chiral-at-Ruthenium Catalyst for Enantioselective Ring-Closing C(sp(3))-H Carbene Insertion to Access Chiral Flavanones, Feng Han, Peter H. Choi, Chen-Xi Ye, Yvonne Grell, Xiulan Xie, Sergei I. Ivlev, and Shuming Chen
Stereodivergent Attached-Ring Synthesis via Non-Covalent Interactions: A Short Formal Synthesis of Merrilactone A, Benjamin J. Huffman, Tiffany Chu, Yusuke Hanaki, Jonathan J. Wong, Shuming Chen, Kendall N. Houk, and Ryan A. Shenvi
Selective skeletal editing of polycyclic arenes using organophotoredox dearomative functionalization, Peng Ji, Cassondra C. Davies, Feng Gao, Jing Chen, Xiang Meng, Kendall N. Houk, Shuming Chen, and Wei Wang
Visible Light-Mediated, Highly Diastereoselective Epimerization of Lactams from the Most Accessible to the More Stable Stereoisomer, Amaan M. Kazerouni, Daniel S. Brandes, Cassondra C. Davies, Laura F. Cotter, James M. Mayer, Shuming Chen, and Jonathan A. Ellman
Pd/NHC-Controlled Regiodivergent Defluorinative Allylation of gem-Difluorocyclopropanes with Allylboronates, Leiyang Lv, Huijun Qian, Anna B. Crowell, Shuming Chen, and Zhiping Li
Facile access to fused 2D/3D rings via intermolecular cascade dearomative [2+2] cycloaddition/rearrangement reactions of quinolines with alkenes, Jiajia Ma, Shuming Chen, Peter Bellotti, Tobias Wagener, Constantin Daniliuc, Kendall N. Houk, and Frank Glorius
Discovery of Potent and Selective Inhibitors against Protein-Derived Electrophilic Cofactors, Xie Wang, Zongtao Lin, Katelyn A. Bustin, Nate R. McKnight, William Parsons, and Megan L. Matthews
Stereocontrolled 1,3-nitrogen migration to access chiral alpha-amino acids, Chen-Xi Ye, Xiang Shen, Shuming Chen, and Eric Meggers
Submissions from 2021
Temperature-Dependent Influence of FliA Overexpression on PHL628 E. coli Biofilm Growth and Composition, Luke D. Buck, Maddison M. Paladino, Kyogo Nagashima, Emma R. Brezel, Joshua S. Holtzman, Sarel J. Urso, and Lisa Ryno
Energy of Concert and Origins of Regioselectivity for 1,3-Dipolar Cycloadditions of Diazomethane, Shuming Chen, Tuo Hu, and K.N. Houk
Accurate Computational Model for the Hydration Extent of Atmospherically Relevant Carbonyls on Aqueous Atmospheric Particles, Matthew J. Elrod, Jane A. Sedlak, and He Ren
Mechanism and Selectivities in Ru-Catalyzed Anti-Markovnikov Formal Hydroalkylation of 1,3-Dienes and Enynes: A Computational Study, Anthony Z. Gao and Shuming Chen
Activity-Based Hydrazine Probes for Protein Profiling of Electrophilic Functionality in Therapeutic Targets, Zongtao Lin, Xie Wang, Katelyn A. Bustin, Kyosuke Shishikura, Nate R. McKnight, Lin He, Radu M. Suciu, Kai Hu, Xian Han, Mina Ahmadi, Erika J. Olson, William Parsons, and Megan L. Matthews
Development of succinimide-based inhibitors for the mitochondrial rhomboid protease PARL, William Parsons, Nicholas T. Rutland, Jennifer A. Crainic, Joaquin M. Cardozo, Alyssa S. Chow, Charlotte L. Andrews, and Brendan K. Sheehan
General Mechanism for Sulfate Radical Addition to Olefinic Volatile Organic Compounds in Secondary Organic Aerosol, He Ren, Jane A. Sedlak, and Matthew J. Elrod
Catalytic alpha-Deracemization of Ketones Enabled by Photoredox Deprotonation and Enantioselective Protonation, Chenhao Zhang, Anthony Gao, Xin Nie, Chen-Xi Ye, Sergei I. Ivlev, Shuming Chen, and Eric Meggers
Submissions from 2020
Determining the Relative Reactivity of Sulfate, Bisulfate and Organosulfates with Epoxides on Secondary Organic Aerosol, Erika Aoki, Jon N. Sarrimanolis, Sophie A. Lyon, and Matthew J. Elrod
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice, Meric Erikci Ertunc, Bernard P. Kok, William Parsons, Justin G. Wang, Dan Tan, Cynthia J. Donaldson, Antonio F.M. Pinto, Joan M. Vaughan, Nhi Ngo, Kenneth M. Lum, Cassandra L. Henry, Aundrea R. Coppola, Micah J. Niphakis, Benjamin F. Cravatt, Enrique Saez, and Alan Saghatelian
Role of AIG1 and ADTRP in Endogenous FAHFA Regulation, Meric Erikci Ertunc, Bernard P. Kok, William Parsons, Justin G. Wang, Dan Tan, Cynthia J. Donaldson, Antonio F.M. Pinto, Joan M. Vaughan, Nhi Ngo, Kenneth M. Lum, Cassandra L. Henry, Aundrea R. Coppola, Micah J. Niphakis, Benjamin F. Cravatt, Enrique Saez, and Alan Saghatelian
Ligand Geometry Directs the Packing and Symmetry of One-Dimensional Helical Motifs in Lead Oxide Naphthoates and Biphenylcarboxylates, Arden C. Hammer, Xiwen Jia, Matthias Zeller, Ezra J. Coughlin, Weiguo Zhang, and Catherine M. Oertel
Efficient Z-Selective Olefin-Acrylamide Cross-Metathesis Enabled by Sterically Demanding Cyclometalated Ruthenium Catalysts, Yan Xu, Jonathan J. Wong, Adrian E. Samkian, Jeong Hoon Ko, Shuming Chen, K.N. Houk, and Robert H. Grubbs
Submissions from 2019
Correction: "Expedient synthesis of eumelanin-inspired 5,6-dihydroxyindole-2-carboxylate ethyl ester derivatives" (2018), Andrew H. Aebly, Jeffrey N. Levy, Benjamin J. Steger, Jonathan C. Quirke, and Jason M. Belitsky
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan, Alice L. Chen, Kenneth M. Lum, Pablo Lara-Gonzalez, Daisuke Ogasawara, Armand B. Cognetta, Alan To, William H. Parsons, Gabriel M. Simon, Arshad Desai, Michael Petrascheck, Liron Bar-Peled, and Benjamin F. Cravatt
Assessing Potential Oligomerization Reaction Mechanisms of Isoprene Epoxydiols on Secondary Organic Aerosol, Santino Stropoli, Corina R. Miner, Daniel Hill, and Matthew Elrod
Chemical comparison of Prunus africana bark and pygeum products marketed for prostate health, Robert Q. Thompson, Daniel Katz, and Brendan Sheehan
Submissions from 2018
Expedient synthesis of eumelanin-inspired 5,6-dihydroxyindole-2-carboxylate ethyl ester derivatives, Andrew H. Aebly, Jeffrey N. Levy, Benjamin J. Steger, Jonathan C. Quirke, and Jason M. Belitsky
Antibody based therapy for ovarian cancer, Yousef Alharbi, Manish S. Patankar, and Rebecca J. Whelan
Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques, Eric Bell, Erica Zheng, and Lisa Ryno
Attraction of Culex pipiens to uropygial gland secretions does not explain feeding preference for American robins, Mary C. Garvin, Amy L. Austin, Norberth H. Stracker, Samuel P. Slowinski, Jordan E. Rutter, Maxwell Butler, Megan Michel, and Rebecca J. Whelan
Assessing the Potential for Oligomer Formation from the Reactions of Lactones in Secondary Organic Aerosols, Kallie Jiang, Daniel R. Hill, and Matthew J. Elrod
Experimental and mathematical evidence that thrombin-binding aptamers form a 1 aptamer:2 protein complex, Kepler S. Mears, Daniel L. Markus, Oluwadamilare Ogunjimi, and Rebecca J. Whelan
Biological Impact and Ethical Implications of Pesticide Use: A Short Module for Upper-Division-Undergraduate Biochemistry Courses, Lisa M. Ryno and Cheryl Cottine
Assessing the Potential Mechanisms of Isomerization Reactions of Isoprene Epoxydiols on Secondary Organic Aerosol, Alex C. Watanabe, Santino J. Stropoli, and Matthew J. Elrod
Submissions from 2017
Kinetics of the Aqueous Phase Reactions of Atmospherically Relevant Monoterpene Epoxides, Diego A. Cortes and Matthew J. Elrod
Catalytic Effect of Solvent Vapors on the Spontaneous Formation of Caffeine–Malonic Acid Cocrystal, Canran Ji, Mikaila C. Hoffman, and Manish A. Mehta
Ligand-Induced Variations in Symmetry and Structural Dimensionality of Lead Oxide Carboxylates, Elaine E. Liu, Calvin Gang, Matthias Zeller, Douglas H. Fabini, and Catherine M. Oertel
Music and materials: Art and science of organ pipe metal, Catherine M. Oertel and Annette Richards
Effects of Cationic Proteins on Gold Nanoparticle/Aptamer Assays, Thomas A. Pires, Conor M. Narovec, and Rebecca J. Whelan
Targeting sigma factor controlled signaling pathwats to modulate biofilm growth and composition, Lisa Ryno, Emma R. Brezel, Sarel J. Loewus, and Erica J. Zheng
Selection of DNA Aptamers for Ovarian Cancer Biomarker CA125 Using One-Pot SELEX and High-Throughput Sequencing, Delia J. Scoville, Tae Kyu Brian Uhm, Jamie A. Shallcross, and Rebecca J. Whelan
Development of a Biological Science Quantitative Reasoning Exam (BioSQuaRE), Liz Stanhope, Laura Zeigler, Tabassum Haque, Laura Le, Marcelo Vinces, Gregory K. Davis, Andrew Zieffler, Peter Brodfuehrer, Marion Preest, Jason M. Belitsky, Charles Umbanhowar Jr., and Paul J. Overvoorde
Gas Phase Oxidation of Campholenic Aldehyde and Solution Phase Reactivity of its Epoxide Derivative, William C. Thomas, William D. Dresser, Diego A. Cortes, and Matthew J. Elrod
A C-13 solid-state NMR investigation of four cocrystals of caffeine and theophylline, Nicolas J. Vigilante and Manish A. Mehta
Exploring inhibitors of the periplasmic chaperone SurA using fluorescence anisotropy, Erica J. Zheng, Eric W. Bell, and Lisa Ryno
Submissions from 2016
Microwave spectra for the three C-13(1) isotopologues of propene and new rotational constants for propene and its C-13(1) isotopologues, Norman C. Craig, Peter Groner, Andrew R. Conrad, Ranil Gurusinghe, and Michael J. Tubergen
Modulation of oxidative stress and subsequent induction of apoptosis and endoplasmic reticulum stress allows citral to decrease cancer cell proliferation, Arvinder Kapur, Mildred Felder, Lucas Fass, Justanjot Kaur, Austin Czarnecki, Kavya Rathi, San Zeng, Kathryn Kalady Osowski, Colin Howell, May P. Xiong, Rebecca J. Whelan, and Manish S. Patankar
Supramolecular Assembly of Tris(4-carboxyphenyl)arenes: Relationship between Molecular Structure and Solid-State Catenation Motifs, Holden W.H. Lai, Ren A. Wiscons, Cassandra A. Zentner, Matthias Zeller, and Jesse L.C. Rowsell
Forensic Chemistry and Its Flip Side, Robert Q. Thompson
Instrumental Investigations: A Laboratory Manual of Forensic Analytical Chemistry, Robert Q. Thompson
Submissions from 2015
Selection of DNA aptamers for ovarian cancer biomarker HE4 using CE-SELEX and high-throughput sequencing, Rachel M. Eaton, Jamie A. Shallcross, Liora E. Mael, Kepler S. Mears, Lisa Minkoff, Delia J. Scoville, and Rebecca J. Whelan
Insights into the Anomalous Vibrational Frequency Shifts of CO 2 Adsorbed to Metal Sites in Microporous Frameworks, Stephen FitzGerald, Jennifer M. Schloss, Christopher J. Pierce, Benjamin Thompson, Jesse L.C. Rowsell, Kuang Yu, and J. R. Schmidt
Hydroxylamine catalyzed Nazarov cyclizations of divinyl ketones, Joseph Z. Hamilton, Nathaniel T. Kadunce, Michael D. McDonald, Laura Rios, and Albert Matlin
Anharmonic Vibrational Analysis of the Infrared and Raman Gas-Phase Spectra of s-trans - and s-gauche -1,3-Butadiene, Sergey V. Krasnoshchekov, Norman C. Craig, Praveenkumar Boopalachandran, Jaan Laane, and Nikolay F. Stepanov
Organosulfate and Nitrate Formation and Reactivity from Epoxides Derived from 2-Methyl-3-buten-2-ol, Liora E. Mael, Michael I. Jacobs, and Matthew J. Elrod
Assessing the Potential for the Reactions of Epoxides with Amines on Secondary Organic Aerosol Particles, Santino J. Stropoli and Matthew J. Elrod
Homocapsaicin: It’s NOT the 7-ene-9-methyl isomer, Robert Q. Thompson
Selection of Aptamers for Ovarian Cancer Biomarkers Informed by Next-Generation Sequencing and Bioinformatics, Rebecca J. Whelan
Selection of DNA aptamers for an ovarian cancer cell line using high-throughput sequencing (Abstract POSTER-THER-1429), Rebecca J. Whelan, Arvinder Kapur, Mildred Felder, Jamie A. Shallcross, Jeff Nie, and Manish S. Patankar
Crystal structure of 2,3-dimethylmaleic anhydride: continuous chains of electrostatic attraction, Ren A. Wiscons, Matthias Zeller, and Jesse L.C. Rowsell
Submissions from 2014
Effects of Structural Differences on the NMR Chemical Shifts in Isostructural Dipeptides, Benjamin D. Altheimer and Manish A. Mehta
Catechol-based coatings inspired by melanin as colorimetric metal-ion sensors, Jason M. Belitsky
Colorimetric metal ion binding of catechol-based coatings inspired by melanin and molecular imprinting, Jason M. Belitsky, Diane S. Lye, Haley R. Gittleman, Thomas A. Gorlin, Arthur N. Gorham, Christine A. Moore, Matthew B. Chaves, and Micah Z. Ellowitz
Mechanistic study of secondary organic aerosol components formed from nucleophilic addition reactions of methacrylic acid epoxide, Adam W. Birdsall, C. R. Miner, Liora E. Mael, and Matthew J. Elrod
Charles M. Hall's patent for refining aluminum metal by electrolysis, Norman C. Craig
Analysis of the rotational structure in the high-resolution infrared spectra of trans-hexatriene-2-d1 and -3-d1, Norman C. Craig, Yihui Chen, Herman van Besien, and Thomas A. Blake
Weak Acidity of Vinyl CH Bonds Enhanced by Halogen Substitution, Norman C. Craig and Albert Matlin
Helical ∞ 1[Pb2O] Chains in Polymorphs of Pb2O(C6H5COO)2, Clay C. Easterday, Liv R. Dedon, Matthias Zeller, and Catherine M. Oertel
MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress, Mildred Felder, Arvinder Kapur, Jesus Gonzalez-Bosquet, Sachi Horibata, Joseph Heintz, Ralph M. Albrecht, Lucas Fass, Justanjot Kaur, Kevin Hu, Hadi Shojaei, Rebecca J. Whelan, and Manish S. Patankar
Infrared overtone spectroscopy of adsorbed hydrogen in MOF-5, Stephen FitzGerald, Jocienne N. Nelson, Elizabeth Gilmour, and Jesse L.C. Rowsell
Kinetics of the reactions of isoprene-derived hydroxynitrates: gas phase epoxide formation and solution phase hydrolysis, Michael I. Jacobs, W. J. Burke, and Matthew J. Elrod
Monitoring Co-Crystal Formation via In Situ Solid-State NMR, Venkata S. Mandala, Sarel J. Loewus, and Manish A. Mehta
Submissions from 2013
Mechanochemical Conversions Between Crystalline Polymorphs of a Complex Organic Solid, Benjamin D. Altheimer, Silvina Pagola, Matthias Zeller, and Manish A. Mehta
Study of the kinetics and equilibria of the oligomerization reactions of 2-methylglyceric acid, Adam W. Birdsall, Cassandra A. Zentner, and Matthew J. Elrod
Kinetics and Thermodynamics of Atmospherically Relevant Aqueous Phase Reactions of α-Pinene Oxide, Dylan B. Bleier and Matthew J. Elrod
Determination of trace level cadmium in SRM 3280 multivitamin/multielement tablets via isotope dilution inductively coupled plasma mass spectrometry, Steven J. Christopher and Robert Q. Thompson
Microwave Spectra of the Deuterium Isotopologues of cis-Hexatriene and a Semiexperimental Equilibrium Structure, Norman C. Craig, Yihui Chen, Hannah A. Fuson, Hengfeng Tian, Herman van Besien, Andrew R. Conrad, Michael J. Tubergen, Heinz Dieter Rudolph, and Jean Demaison
Analysis of the rotational structure in the high-resolution infrared spectra of cis,cis- and trans,trans-1,4-difluorobutadiene-1-d1 and trans,trans-1,4-difluorobutadiene-1,4-d2, Norman C. Craig, Yihui Chen, Yuhua Lu, Christopher F. Neese, Deacon J. Nemchick, and Thomas A. Blake
Highly Selective Quantum Sieving of D2 from H2 by a Metal–Organic Framework As Determined by Gas Manometry and Infrared Spectroscopy, Stephen FitzGerald, Christopher J. Pierce, Jesse L.C. Rowsell, Eric D. Bloch, and Jarad A. Mason
Criteria for Spontaneous Processes Derived from the Global Point of View, Eric A. Gislason and Norman C. Craig
Rate Constants and Products of the OH Reaction with Isoprene-Derived Epoxides, Michael I. Jacobs, Adam I. Darer, and Matthew J. Elrod
Anharmonic Vibrational Analysis of the Gas-Phase Infrared Spectrum of 1,1-Difluoroethylene Using the Operator Van Vleck Canonical Perturbation Theory, Sergey V. Krasnoshchekov, Norman C. Craig, and Nikolay F. Stepanov
Computational Study of the Cyclization of 5-Hexenyl, 3-Oxa-5-hexenyl and 4-Oxa-5-hexenyl Radicals, Albert Matlin and Matthew C. Leyden
Novel separation for the determination of cadmium by isotope dilution ICP-MS in samples containing high concentrations of molybdenum and tin, Robert Q. Thompson and Steven J. Christopher
Submissions from 2012
Small molecule modulators of aggregation in synthetic melanin polymerizations, Jason M. Belitsky, Micah Z. Ellowitz, Diane S. Lye, and Alexander L. Kilbo
Gas-Phase Raman Spectra of s-trans- and s-gauche-1,3-Butadiene and Their Deuterated Isotopologues, Praveenkumar Boopalachandran, Norman C. Craig, and Jaan Laane
