Sorption Behavior and Sunlight-Driven Photolysis of Fluorinated Pharmaceuticals (Efavirenz, Fluoxetine, and Sitagliptin) in Aqueous Environments

Location

Bent Corridor, Science Center

Document Type

Poster - Oberlin Community Only

Start Date

5-1-2026 12:00 PM

End Date

5-1-2026 2:00 PM

Research Program

Oberlin (Bio)Chemistry Summer Research

Abstract

Fluorinated compounds are of increasing concern in natural bodies of water due to their high stability and persistence. One of the major pathways through which they enter the surface water environment is through prescribed pharmaceuticals. Fluorinated pharmaceuticals can be removed from surface water through degradation driven by sunlight, but the exact mechanisms and rates are not well understood. Furthermore, we suspect that photodegradation of fluorinated pharmaceuticals leads to the production of persistent transformation products such as trifluoroacetic acid (TFA). Additionally, in water treatment plants, sorbents can be used to remove similar contaminants such as per- and polyfluoroalkyl substances (PFAS), but the efficacy of this strategy in removing fluorinated pharmaceuticals is unknown. We simulated both photochemical and sorption processes in the laboratory to understand the fate and transport of three fluorinated pharmaceuticals (efavirenz, fluoxetine, and sitagliptin) in aqueous environments. From our data, we are able to better predict the impacts of fluorinated pharmaceuticals on natural and built environments.

Keywords:

Environmental chemistry, Pollutants, Pharmaceuticals, Water quality

Notes

Presenters: Taylor Satterfield, Samantha Taylor, and Ingrid Vigsnes

Access to the poster is available to Oberlin College users only.

Major

3-2 Engineering

Project Mentor(s)

Bailey Bowers, Chemistry and Biochemistry

2026

This document is currently not available here.

Share

COinS
 
May 1st, 12:00 PM May 1st, 2:00 PM

Sorption Behavior and Sunlight-Driven Photolysis of Fluorinated Pharmaceuticals (Efavirenz, Fluoxetine, and Sitagliptin) in Aqueous Environments

Bent Corridor, Science Center

Fluorinated compounds are of increasing concern in natural bodies of water due to their high stability and persistence. One of the major pathways through which they enter the surface water environment is through prescribed pharmaceuticals. Fluorinated pharmaceuticals can be removed from surface water through degradation driven by sunlight, but the exact mechanisms and rates are not well understood. Furthermore, we suspect that photodegradation of fluorinated pharmaceuticals leads to the production of persistent transformation products such as trifluoroacetic acid (TFA). Additionally, in water treatment plants, sorbents can be used to remove similar contaminants such as per- and polyfluoroalkyl substances (PFAS), but the efficacy of this strategy in removing fluorinated pharmaceuticals is unknown. We simulated both photochemical and sorption processes in the laboratory to understand the fate and transport of three fluorinated pharmaceuticals (efavirenz, fluoxetine, and sitagliptin) in aqueous environments. From our data, we are able to better predict the impacts of fluorinated pharmaceuticals on natural and built environments.