Event Title

Luteinizing Hormone and the Brain: A Role for Brain-Derived Neurotrophic Factor

Location

King Building 343

Start Date

4-29-2016 4:00 PM

End Date

4-29-2016 5:15 PM

Abtract

Memory loss and other forms of cognitive decline are prevalent in post-menopausal women due in part to changes in hormonal levels. Accordingly, estrogen treatment improves cognition—but not without harmful side effects. This has led to research into other hormones on the same axis including luteinizing hormone (LH), which is present at high levels both in humans and in a post-menopausal rat model. Previously, the Thornton lab has found that lowering LH levels with the drug Antide rescues spatial memory. My honors project examines the role of brain-derived neurotrophic factor, a well-characterized player in cognition, in mediating the effects of LH and Antide on memory.

Notes

Session III, Panel 17 - Meditations on Motivation, Mastery, and Memory
Moderator: Cindy Frantz, Associate Professor of Psychology

Major

Neuroscience

Advisor(s)

Jan Thornton, Neuroscience

Project Mentor(s)

Jan Thornton, Neuroscience

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Apr 29th, 4:00 PM Apr 29th, 5:15 PM

Luteinizing Hormone and the Brain: A Role for Brain-Derived Neurotrophic Factor

King Building 343

Memory loss and other forms of cognitive decline are prevalent in post-menopausal women due in part to changes in hormonal levels. Accordingly, estrogen treatment improves cognition—but not without harmful side effects. This has led to research into other hormones on the same axis including luteinizing hormone (LH), which is present at high levels both in humans and in a post-menopausal rat model. Previously, the Thornton lab has found that lowering LH levels with the drug Antide rescues spatial memory. My honors project examines the role of brain-derived neurotrophic factor, a well-characterized player in cognition, in mediating the effects of LH and Antide on memory.