Event Title

HIV Cell Entry and Genetic Host Factors

Presenter Information

Inyang Udo-Inyang

Location

Science Center, K209

Document Type

Presentation

Start Date

4-27-2012 4:00 PM

End Date

4-27-2012 5:00 PM

Abstract

The HIV-1 virus has shown the ability to use two co-receptors to gain entry into the host cell: either the CCR5 or the CXCR4 chemokine co-receptors (or both). It remains unclear what determines the preference of some HIV-1 viruses for the CCR5 co-receptor and what causes the progression to use CXCR4 over the course of infection. This research project aims to examine the role of genetic host factors in virus tropism.

Notes

Session III, Panel 6: From Fertilization to Infection: Studies of Cellular Action
Moderator: Taylor Allen, Associate Professor of Biology

Major

Biochemistry

Advisor(s)

William H. Fuchsman, Chemistry and Biochemistry

Project Mentor(s)

Timothy Henrich, Brigham and Women's Hospital, Harvard Medical School

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Apr 27th, 4:00 PM Apr 27th, 5:00 PM

HIV Cell Entry and Genetic Host Factors

Science Center, K209

The HIV-1 virus has shown the ability to use two co-receptors to gain entry into the host cell: either the CCR5 or the CXCR4 chemokine co-receptors (or both). It remains unclear what determines the preference of some HIV-1 viruses for the CCR5 co-receptor and what causes the progression to use CXCR4 over the course of infection. This research project aims to examine the role of genetic host factors in virus tropism.