Event Title

Establishment of In Vitro Culture System Using Human Induced Pluripotent Stem Cell-Derived Neural and Non-Neural Cells

Presenter Information

Alyssa Altheimer, Oberlin College

Location

Science Center, Bent Corridor

Start Date

10-28-2016 5:30 PM

End Date

10-28-2016 6:00 PM

Research Program

Icahn School of Medicine at Mount Sinai

Poster Number

5

Abstract

For many years, neuroscientists have been limited in their studies of CNS disorders, such as Alzheimer’s and schizophrenia, by a lack of live human brain cells. However, Kristen Brennand’s laboratory at Mount Sinai’s School of Medicine circumvents this obstacle by reprogramming skin cells from patients with or without schizophrenia and Alzheimer’s disease into stem cells, and then differentiating those stem cells into various brain cells. Then, the genetics, morphology, and chemistry of those cells can be studied. This summer, I interned with Julia TCW, a postdoctoral fellow in Brennand lab, from whom I learned the following techniques. (In the poster, my abstract is followed by an introduction into what the lab does and then some techniques I learned in the lab.)

Major

Undeclared

Project Mentor(s)

Julia TCW and Kristen Brennand (Neuroscience), Icahn School of Medicine at Mount Sinai

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Oct 28th, 5:30 PM Oct 28th, 6:00 PM

Establishment of In Vitro Culture System Using Human Induced Pluripotent Stem Cell-Derived Neural and Non-Neural Cells

Science Center, Bent Corridor

For many years, neuroscientists have been limited in their studies of CNS disorders, such as Alzheimer’s and schizophrenia, by a lack of live human brain cells. However, Kristen Brennand’s laboratory at Mount Sinai’s School of Medicine circumvents this obstacle by reprogramming skin cells from patients with or without schizophrenia and Alzheimer’s disease into stem cells, and then differentiating those stem cells into various brain cells. Then, the genetics, morphology, and chemistry of those cells can be studied. This summer, I interned with Julia TCW, a postdoctoral fellow in Brennand lab, from whom I learned the following techniques. (In the poster, my abstract is followed by an introduction into what the lab does and then some techniques I learned in the lab.)